When Curious George is offered a special space mission, Ted (The Man in the Yellow Hat) can’t deny his little friend this exciting journey, especially after Curious George completes the training. But when he crash-lands in Africa, a worried Ted goes searching, expecting the worst, only to have it turn out to be the best.
A half-striped zebra is blamed for the drought and leaves his herd in search of his missing stripes. He is joined on his quest by an overprotective wildebeest and a flamboyant ostrich; they defeat the tyrannical leopard and save his herd.
BSAA Chris Redfield enlists the help of government agent Leon S. Kennedy and Professor Rebecca Chambers from Alexander Institute of Biotechnology to stop a death merchant with a vengeance from spreading a deadly virus in New York.